张林启，广州医科大学附属肿瘤医院核医学科，主治医师，硕士生导师,美国埃默里大学访问学者
基本情况简介：
在广州医科大学附属肿瘤医院核医学科工作十余年，担任，广州市医师学会核医学与分子影像分会副主任委员，广东省医学会核医学分会青年委员。主持国家和省部级课题3项，发表论文30余篇。
联系方式: 邮箱zhanglinqi0909@163.com；
研究领域
1、肝脏恶性肿瘤诊疗分子影像可视化研究
2、新型PET分子探针研发
科研项目
1. 国家自然科学基金委员会，青年项目，82101994，基于多频率3D磁共振弹性成像技术早期预测肝细胞癌靶向治疗响应的定量可视化研究，2022-01至2024-12，30万
2. 广东省自然科学基金，面上项目，2024A1515011956, 基于多模态影像技术可视化肿瘤微环境变化早期预测肝癌免疫治疗耐药及逆转策略，2024-1至2026-12，15万
3. 广州医科大学附属肿瘤医院，临床研究5555计划基金；先进项目；IIT-2022-015(HYX)；18F-FDG PET/CT及18F-FAPI PET/CT对恶性肿瘤诊断的前瞻性对比研究，2023年2月至2026年2月，15万
4. 广州医科大学附属肿瘤医院，人才培养项目，飞鹰人才，基于谷氨酰胺代谢PET显像早期预测肝细胞癌免疫治疗响应的定量可视化研究，2023年7月至2026年7月，8万
5. 广东省自然科学基金，面上项目，2019A1515010845，基于多模态影像技术探索宫颈癌放疗后机能不全性骨折演变的机制研究，2019-10至2022-09，10万
代表性论著（*第一作者，#通讯作者）
1. Jing Zhang#, Qiao He#, Shuqin Jiang#, Mengsi Li, Haibao Xue, Donghui Zhang, Shuyi Li, Hao Peng, , Jiuceng Liang, Zhidong Liu, Songquan Rao, Jin Wang, Rusen Zhang*, Linqi Zhang*.18F-FAPI PET/CT in the Evaluation of Focal Liver Lesions with Non18F-FDG Avidity.Eur J Nucl Med Mol Imaging, 2023, 50: 937–950 .(SCIE，IF: 8.6 )
2. Jiucen Liang#, Shuqin Jiang#, Jingjing Song#, Danyang Chen, Shaojuan Weng, Shuyi Li, Hao Peng, Zhidong Liu, Jing Zhang, Yuanlin Chen, Songquan Rao, Haipeng Chen, Rusen Zhang*, Hao Liu*, Linqi Zhang*. Role of [18F]FAPI-04 in staging and therapeutic management of intrahepatic cholangiocarcinoma: prospective comparison with [18F]FDG PET/CT. EJNMMI Res, 2024, 14(1):81. (SCIE，IF: 3.1)
3. Jiucen Liang#, Jing Zhang#, Jingjing Song, Rusen Zhang, Linqi Zhang*. Intense 18F-FAPI Uptake in Small Recurrent Lesions of Combined Hepatocellular-Cholangiocarcinoma Negative on 18F-FDG PET/CT. Clin Nucl Med, 2024,49(7):e351-e353. (SCIE，IF: 10)
4. Jing Zhang#, Shuqin Jiang#, Mingsi Li#, Haibao Xue, Xi Zhong, Shuyi Li, Hao Peng, Jiuceng Liang, Zhidong Liu, Songquan Rao, Haipeng Chen, Zewen Cao, Yuanfeng Gong, Guoshuo Chen, Rusen Zhang*, Linqi Zhang*. Head-to-head comparison of 18F-FAPI and 18F-FDG PET/CT in staging and therapeutic management of hepatocellular carcinoma.Cancer Imaging. 2023, 23(1):106. (SCIE，IF: 3.5)
5. Jing Zhang#, Shuqin Jiang#, Rusen Zhang, Linqi Zhang*. Increased 18F-FAPI Uptake in Radiation Induced Liver Injury.Clin Nucl Med, 2023;48: e474–e476. (SCIE，IF: 10)
6. Linqi Zhang#, Zhidong Liu#, Shuqin Jiang, Qiao He, Rusen Zhang*.68Ga-FAPI Versus 18F-FDG PET/CT in Recurrent Undifferentiated Pleomorphic Sarcoma of Colon Mesentery.Clin Nucl Med, 2022; 47: e651–e653. (SCIE，IF: 10).
7. Linqi Zhang#, Xi Long#, Mayidili Nijiati, Tianhui Zhang, Mengsi Li, Ying Deng, Sichi Kuang, Yuanqiang Xiao, Jie Zhu, Bingjun He, Jingbiao Chen, Phillip Rossman, Kevin J Glaser, Sudhakar K Venkatesh, Richard L Ehman, Jin Wang*. Tumor stiffness measured by 3D magnetic resonance elastography can help predict the aggressiveness of endometrial carcinoma: preliminary findings. Cancer Imaging, 2021, 21(1):50. (SCIE，IF: 3.5)
8. Linqi Zhang#, Sichi Kuang#, Jingbiao Chen, Yao Zhang, Binliang Zhao, Hao Peng, Yuanqiang Xiao, Kathryn Fowler, Jin Wang*, Claude B Sirlin. The Role of Preoperative Dynamic Contrast-enhanced 3.0-T MR Imaging in Predicting Early Recurrence in Patients With Early-Stage Hepatocellular Carcinomas After Curative Resection. Front Oncol, 2019; 9:1336. (SCIE，IF: 3.5)
9. Linqi Zhang#, Qiao He#, Tao Zhou, Rusen Zhang*. Incidental Detection of Ovarian Thecoma by 99mTc-MDP Whole-Body Bone Scan: Contribution of Hybrid SPECT/CT. Clin Nucl Med 2019; 44: e577–e578. (SCIE，IF: 10)
10. Linqi Zhang#, Qiao He#, Tao Zhou, Bin Zhang, Wei Li, Hao Peng, Xi Zhong, Liwu Ma, Rusen Zhang*. Accurate characterization of (99m) Tc-MDP uptake in extraosseous neoplasm mimicking bone metastasis on whole-body bone scan: contribution of SPECT/CT. BMC Med Imaging, 2019;19(1): 44. (SCIE，IF: 2.9)
11. Linqi Zhang#, Qiao He#, Ming Jiang, Bin Zhang, Xi Zhong, Rusen Zhang*. Diagnosis of Insufficiency Fracture After Radiotherapy in Patients With Cervical Cancer: Contribution of Technetium 99mTc -Labeled Methylene Diphosphonate Single-Photon Emission Computed Tomography/Computed Tomography. Int J Gynecol Cancer, 2018; 28(7): 1369-76. (SCIE，IF: 4.5)
12. Linqi Zhang, Xu Zhang, Rusen Zhang, Wei Fan*. The role of initial 18F-FDG PET/CT in the management of patients with suspected extramedullary plasmocytoma. Cancer Imaging, 2018; 18 (1):19. (SCIE，IF: 3.5)
13. Linqi Zhang#, Qiao He#, Wei Li, Rusen Zhang*. The value of (99m) Tc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia. BMC Med Imaging, 2017;17(1): 46. (SCIE，IF: 2.9)
14. Linqi Zhang, Xu Zhang, Rusen Zhang, Fan Wei*. 18F-FDG PET/CT Metabolic Activity in a Patient With Solitary Extramedullary Plasmacytoma of the Lung. Clin Nucl Med, 2016; 41(3): 232-234. (SCIE，IF: 10)
15. Xi Zhong#, Linqi Zhang#, Tianfa Dong#, Hui Mai, Bingui Lu, Lu Huang and Jiansheng Li1*.Clinical and MRI features of sacral insufciency fractures after radiotherapy in patients with cervical cancer. BMC Womens Health 2022. 22:166. (SCIE，IF: 2.742)
16. Hao Peng#, Linqi Zhang#, Tao Zhou, Wen Li, Wei Li, Liwu Ma, Rusen Zhang*. Characterization of Solitary Lesions in the Extremities on Whole-Body Bone Scan in Patients With Known Cancer: Contribution of Single-Photon Emission Computed Tomography/Computed Tomography. Front Oncol, 2019, 9: 607. (SCIE，IF: 3.5)
17. Qiao He#, Linqi Zhang#, Bing Zhang , Xiangsong Zhang*. Use of 18F-FDG PET/CT for the Evaluation of Carcinoma Arising From Choledochal Cysts. Clin Nucl Med, 2019; 44(1): e51-e53. (SCIE，IF: 10)
18. Qiao He#, Linqi Zhang#, Bing Zhang, Xinchong Shi, Chang Yi, Xiangsong Zhang*. Diagnostic accuracy of 13N-ammonia PET, 11C-methionine PET and 18Ffluorodeoxyglucose PET: a comparative study in patients with suspected cerebral glioma. BMC Cancer, 2019; 19: 332. (SCIE，IF: 3.4)
19. Qiao He# , Bing Zhang#, Linqi Zhang*, Zhifeng Chen , Xinchong Shi , Chang Yi , Xiaoyan Wang , Xiangsong Zhang*. Diagnostic efficiency of 68Ga-DOTANOC PET/CT in patients with suspected tumour-induced osteomalacia. Eur Radiol, 2021; 31:2414-2421. (SCIE，IF: 4.7)
20. Qiao He#, Zhengkun Zhang#, Linqi Zhang#, Bing Zhang, Yali Long, Yuying Zhang, Zhihong Liao, Zhihao Zha*, Xiangsong Zhang*. Head-to-head comparison between [68Ga]Ga-DOTA-NOC and [18F]DOPA PET/CT in a diverse cohort of patients with pheochromocytomas and paragangliomas. Eur J Nucl Med Mol Imaging. 2024. 51:1989–2001. (SCIE，IF: 8.6）
